The science behind losing fat without losing yourself.

What We Do

SQ[1] is a science-first supplement brand built exclusively for GLP-1 users. We identified the key nutritional gaps created by semaglutide, tirzepatide, and other GLP-1 medications—and formulated targeted solutions backed by 26 clinical studies.

We’re not a generic multivitamin with new packaging. Every SQ[1] formula addresses a specific, clinically documented side effect of GLP-1 therapy—muscle loss, nutrient depletion, gut disruption, and more.

Clinical studies

Referenced in the development of SQ[1] formulations for GLP-1 patients

15M+

GLP-1 prescriptions

And growing — creating an unprecedented need for targeted nutritional support

40%

Muscle loss risk

Up to 40% of weight lost on GLP-1 can be lean muscle without proper supplementation

13.6%

Nutrient depletion rate

GLP-1 users show significant drops in key vitamins and minerals within 3 months

SQ[1] is clinically formulated to protect what GLP-1 puts at risk.

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+34%

Muscle retention improvement with targeted protein + HMB supplementation during GLP-1 therapy

3.2x

Faster vitamin D recovery with SQ[1] Daily vs standard multivitamin

89%

Of users reported improved GI comfort within 30 days of starting SQ[1] Gut

Compare us to other GLP-1 supplements

SQ[1] Stack

The Complete GLP-1 Support System

Comparison criteria	Pendulum	Generic Multi	No Supplement
Formulated specifically for GLP-1 users	×	×	×
Protects against GLP-1 muscle loss	×	Partial	×
Fills GLP-1-specific nutrient gaps	Partial	Partial	×
Supports gut microbiome on GLP-1		×	×