The research behind nutrition during rapid weight loss.
![The research behind SQ[1] nutrition](/_next/image?url=%2Fimages%2Fscience-hero.jpg&w=3840&q=75&dpl=dpl_8QRzj4TMztiGYNZ44tHwvEKsvWBL)
SQ[1] is a research-led supplement brand for people focused on nutrition during rapid weight loss. We reviewed the published research on common nutritional gaps during weight management and built targeted formulas around it.
We’re not a generic multivitamin with new packaging. Every SQ[1] formula is designed around specific nutritional needs — supporting muscle maintenance, filling common nutrient gaps, and promoting digestive comfort.*
The STEP 1 trial (Wilding 2021) showed 14.9% mean weight loss with semaglutide, while Prado et al. (2024) estimated 25–39% of that loss is fat-free mass. These findings shaped every SQ[1] formula.
View all 26 cited studies →Research-led
Ingredient selection
Every ingredient chosen based on peer-reviewed literature on nutrition during rapid weight loss
15M+
GLP-1 prescriptions
A growing population with unique nutritional needs during weight management
Therapeutic
Doses
Active ingredients delivered at doses studied in published research — not token amounts
Third-party
Tested
Every batch independently tested for purity, potency, and contaminants
Formulated to support your body during rapid weight loss.*
Shop nowProtein + HMB
Formulated with whey isolate and HMB — nutrients studied for their role in supporting muscle maintenance during weight management.*
Vitamin D3
SQ[1] Nourish provides vitamin D3 to help maintain healthy vitamin D levels already within the normal range.*
Probiotic blend
A targeted probiotic, prebiotic, and ginger blend formulated to support digestive comfort.*
Why GLP-1 Users Switch to SQ[1] — and Don’t Go Back
| Comparison criteria | SQ[1] | Pendulum | Generic Multi | No Supplement |
|---|---|---|---|---|
| Formulated specifically for GLP-1 users | × | × | × | |
| Protects against GLP-1 muscle loss | × | Partial | × | |
| Fills GLP-1-specific nutrient gaps | Partial | Partial | × | |
| Supports gut microbiome on GLP-1 | × | × |
Research-led
Ingredient selection
Every ingredient chosen based on peer-reviewed literature on nutrition during rapid weight loss
15M+
GLP-1 prescriptions
A growing population with unique nutritional needs during weight management
Therapeutic
Doses
Active ingredients delivered at doses studied in published research — not token amounts
Third-party
Tested
Every batch independently tested for purity, potency, and contaminants
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Consult your healthcare provider before starting any new supplement, especially if you are taking prescription medication.