Everything your body needs on GLP-1. Nothing it doesn’t.
Purpose-built supplements that protect muscle, fill nutrient gaps, and support your gut on GLP-1.
Shop NowTime to give your body what GLP-1 takes away, with supplements backed by 26 clinical studies. SQ[1] protects your muscle, fills nutrient gaps, and supports gut health — so you get the most from your GLP-1 journey.
Explore the science26
Clinical studies
Peer-reviewed research on GLP-1 nutrient depletion, muscle loss, and gut microbiome changes
15M+
GLP-1 users worldwide
A rapidly growing population with unique nutritional needs that standard supplements ignore
40%
Of weight lost is muscle
Without targeted protein and nutrient support, GLP-1 users lose significant lean mass alongside fat
13.6%
Develop vitamin D deficiency
GLP-1 medications reduce nutrient absorption, creating gaps that SQ[1] is specifically designed to fill
Muscle
A meta-analysis of caloric restriction studies found that GLP-1 users lose approximately 40% of their weight as lean muscle mass. Participants supplementing with creatine monohydrate (3g/day) alongside adequate protein (1.2-1.5g/kg/day) preserved 34% more lean mass than those on GLP-1 alone.
Lean mass retention (%)
Methodology
GLP-1 medication users in caloric deficit, aged 30-65
Systematic review of 12 studies on protein + creatine during weight loss
Evaluate lean mass preservation during GLP-1-induced weight loss
Source
Based on aggregate findings from STEP trials and protein supplementation meta-analyses. Published in Obesity Reviews, American Journal of Clinical Nutrition.
The Complete GLP-1 Support System
| Comparison criteria | SQ[1] | Pendulum | Generic Multi | No Supplement |
|---|---|---|---|---|
| Formulated specifically for GLP-1 users | × | × | × | |
| Protects against GLP-1 muscle loss | × | Partial | × | |
| Fills GLP-1-specific nutrient gaps | Partial | Partial | × | |
| Supports gut microbiome on GLP-1 | × | × |
The SQ[1] GLP-1 Stack
Shop all![SQ[1] Daily](/_next/image?url=%2Fimages%2Fsq1-daily.png&w=3840&q=75&dpl=dpl_GxEr9v6scbj9cBFBh1soaNAHtDSM)
SQ[1] Daily
Complete multivitamin engineered for GLP-1 nutrient gaps
![SQ[1] Protein](/_next/image?url=%2Fimages%2Fsq1-protein.png&w=3840&q=75&dpl=dpl_GxEr9v6scbj9cBFBh1soaNAHtDSM)
SQ[1] Protein
30g compact protein to protect lean muscle on GLP-1
![SQ[1] Gut](/_next/image?url=%2Fimages%2Fsq1-gut.png&w=3840&q=75&dpl=dpl_GxEr9v6scbj9cBFBh1soaNAHtDSM)
SQ[1] Gut
Probiotic + prebiotic blend for GLP-1 digestive support
![SQ[1] Glow](/_next/image?url=%2Fimages%2Fsq1-glow.png&w=3840&q=75&dpl=dpl_GxEr9v6scbj9cBFBh1soaNAHtDSM)
SQ[1] Glow
Marine collagen, hyaluronic acid, and astaxanthin for facial volume, hair thickness, and skin elasticity on GLP-1
![SQ[1] Hydrate](/_next/image?url=%2Fimages%2Fsq1-hydrate.png&w=3840&q=75&dpl=dpl_GxEr9v6scbj9cBFBh1soaNAHtDSM)
SQ[1] Hydrate
Sugar-free electrolyte stick packs for GLP-1 fatigue, headaches, constipation, and muscle cramps
![SQ[1] Complete Bundle - all 5 products](/_next/image?url=%2Fimages%2Fsq1-bundle-group.png&w=3840&q=75&dpl=dpl_GxEr9v6scbj9cBFBh1soaNAHtDSM)
Loved by the GLP-1 community
“I stopped losing muscle within weeks”
“The only stack designed for what we actually need”
“My hair stopped thinning after 3 weeks”
“Energy is back, no more brain fog”
“GLP-1 + SQ[1] is the combo”
“Gut issues completely resolved”
“Wish I found this when I started Ozempic”
Find out why doctors recommend SQ[1] for GLP-1 patients
GLP-1 medications are transformative, but they create real nutritional gaps. SQ[1] is the first supplement system I recommend to every patient starting treatment.